19th of October 2025

Continuous Glucose Monitoring and the Science of Longevity


Understanding its promise, limitations, and the physician-led difference


CGM has moved beyond diabetes care. Used thoughtfully, it becomes a dynamic biomarker of metabolic resilience—used superficially, it’s just noise.




Why track glucose if you’re not diabetic?



Healthy adults typically maintain glucose in a narrow range most of the day.

Even within “normal”, post-meal spikes, day-to-day variability and overnight stability differ meaningfully between people.

Repeated sharp excursions and late-evening drift are increasingly linked with oxidative stress, vascular ageing and metabolic inflexibility.


Short, focused CGM cycles (10–14 days) can show:


  • how everyday meals affect post-prandial area under the curve (AUC)

  • whether late eating reduces overnight recovery

  • how stress or sleep debt destabilise glucose



Reference points from healthy cohorts:

Mean glucose ≈ 5.0 mmol/L  |  Variability (CV) < 14–15 %  |  Time-in-range > 94 %

These are not rigid targets, but useful context for understanding your own data.




Consumer CGM apps: usefulness and drawbacks



The popularity of ZOE and Lingo has brought CGM into the wellness space.

Both have benefits—and predictable limitations.


ZOE — awareness through nutrition science

Combines a 14-day CGM with gut-microbiome and lipid testing to create personalised food scores.

Excellent for awareness, but interpretation is app-led; spikes can reflect timing, stress, or hormonal changes as much as food itself.


Lingo (Abbott)

Focuses on real-time feedback with a simplified daily “Lingo Count”.

Good for habits and accessibility, but still a consumer tool—data depth and clinical context are limited.


Bottom line:

Apps like these are valuable for awareness, but true optimisation requires medical interpretation and context.

Goal

ZOE

Lingo

Physician-led CGM

Focus

Nutrition awareness

Real-time habit feedback

Clinical interpretation & optimisation

Strength

Microbiome + food scoring

Simple daily nudges

AUC/CV analysis, circadian mapping

Limitation

App-led, less context

Consumer framing

Requires consultation, purposeful use

Best for

Food education

Habit formation

Precision longevity goals



When CGM adds the most value



  • Analysing AUC after real meals (not only test foods)

  • Comparing early vs late eating and overnight recovery

  • Relating changes to stress, caffeine, exercise, alcohol

  • Integrating data with genomics, sleep and HRV



It’s least helpful when used indefinitely without a goal, or when people chase a single “perfect” number.




How I use CGM differently



  • Clinical interpretation first: AUC, variability and circadian patterns benchmarked against healthy non-diabetic reference data.

  • Context always matters: Findings are integrated with genomics (if available), sleep, HRV, training load and the broader health picture.

  • Actionable and sustainable: Simple, elegant adjustments that stabilise glucose without unnecessary restriction.





Who I recommend CGM to



  • Performance-minded professionals or athletes seeking steadier energy and metabolic flexibility

  • Those stuck despite disciplined habits (plateaus, cravings, fatigue)

  • Clients on structured longevity programmes (fasting, peptide or NAD⁺ protocols) where timing and safety depend on metabolic insight